anti glomerular basement membrane antibody glomerular basement membraneThe anti glomerular basement membrane anti GBM test looks for anti glomerular basement membrane antibodies that attack a part of the kidney known as the glomerular basement membrane GBM anti glomerular basement membrane antibody medlineplus gov Medical EncyclopediaThe glomerular basement membrane is the part of the kidney that helps filter waste and extra fluid from the blood Anti glomerular basement membrane antibodies are antibodies against this membrane They can lead to kidney damage
glomerular basement membrane Anti glomerular basement membrane antibody anti GBM Ab is an antibody which is found in Goodpasture s syndrome but not found in microscopic polyangiitis Some sources consider anti GBM disease and Goodpasture disease to be synonymous terms describing histological presentation reserving the term Goodpasture syndrome for clinical presentation anti glomerular basement membrane antibody ncbi nlm nih gov Journal List NPG Open AccessAs the pathogenesis of anti GBM GN became clear treatment regimens were designed to remove the circulating pathogenic antibody that caused the disease suppress further synthesis of this pathogenic antibody and attenuate the glomerular inflammatory response initiated by the anti GBM antibody ltd aruplab tests pub 0049191May be useful in detecting glomerular basement membrane GBM antibodies Combined use of IFA Glomerular Basement Membrane Antibody IgG by Multiplex Bead Assay and IFA may improve diagnostic sensitivity for disease If positive may be useful for monitoring treatment response
and microbiology Anti glomerular basement membrane antibody anti GBM disease or Goodpasture syndrome is a rare autoimmune disease characterized by the presence of autoantibodies directed against the NC1 domain of the alpha 3 chain of basement membrane collagen type IV anti glomerular basement membrane antibody ltd aruplab tests pub 0049191May be useful in detecting glomerular basement membrane GBM antibodies Combined use of IFA Glomerular Basement Membrane Antibody IgG by Multiplex Bead Assay and IFA may improve diagnostic sensitivity for disease If positive may be useful for monitoring treatment response
anti glomerular basement membrane antibody Gallery
anti gbm basement membrane, image source: unckidneycenter.org
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PMC3477576_JBB2012 417675, image source: openi.nlm.nih.gov
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