20 Fresh Antiglomerular Basement Membrane Disease

antiglomerular basement membrane disease glomerular basement membrane anti GBM disease is a rare small vessel vasculitis that affects glomerular capillaries where it may result in glomerular necrosis and crescent formation pulmonary capillaries where it may cause alveolar hemorrhage or both antiglomerular basement membrane disease basement membrane diseaseAntiglomerular basement membrane anti GBM disease Goodpasture syndrome is an autoimmune condition characterized by progressive damage to collagen resulting in damage to the lung parenchyma and the kidney basement membrane Lung damage results in hemorrhage with cough and shortness of Published in web science 2003Authors Charles D PuseyAffiliation Imperial College LondonAbout Kidney Prednisolone Bullous pemphigoid Human leukocyte antigen Pulmonary he

medlineplus gov Medical EncyclopediaThe glomerular basement membrane is the part of the kidney that helps filter waste and extra fluid from the blood Anti glomerular basement membrane antibodies are antibodies against this membrane They can lead to kidney damage antiglomerular basement membrane disease glomerular basement membrane disease Principal discussant Charles D Pusey Hammersmith Hospital and Imperial College London London United Kingdom CASE PRESENTATION A 47 year oldwhite manwho workedas aprofessional musi cian presented glomerular basement membraneThe anti glomerular basement membrane anti GBM test looks for anti glomerular basement membrane antibodies that attack a part of the kidney known as the glomerular basement membrane GBM

jasn asnjournals content 10 11 2446 fullAnti glomerular basement membrane disease anti GBM is a rare but well characterized cause of glomerulonephritis It is defined by the presence of autoantibodies directed at specific antigenic targets within the glomerular and or pulmonary basement membrane Published in Journal of The American Society of Nephrology 1999Authors David C Kluth Andrew J ReesAbout Glomerulonephritis Immunopathology Alport syndrome Autoimmune disease Imm antiglomerular basement membrane disease glomerular basement membraneThe anti glomerular basement membrane anti GBM test looks for anti glomerular basement membrane antibodies that attack a part of the kidney known as the glomerular basement membrane GBM basement membrane disease must be differentiated from the other two common causes of glomerular hematuria IgA nephropathy and Alport syndrome The history and presentation are helpful in this regard In Alport syndrome there is often a family history of kidney failure which may be associated with hearing impairment Specialty UrologySigns and symptoms Genetics Diagnosis Treatment Prognosis

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