glomerular basement membrane thickness of glomerular basement membrane GBM thickness in children with minimal change nephrotic syndrome were made on electron micrographs of 43 biopsy specimens obtained from 35 children aged 1 13 years of whom 13 were in remission at the time of biopsy glomerular basement membrane thickness glomerular basement membrane GBM of the kidney is the basal lamina layer of the glomerulus The glomerular endothelial cells the GBM and the filtration slits between the podocytes perform the filtration function of the glomerulus separating the blood in the capillaries from the FMA 74274MeSH D050533Layers Pathology
international article S0085 2538 15 48624 7 Fig 2 Glomerular basement membrane GBM thickness increases throughout childhood with the rate of increase declining from approxi The direct measurement technique entails 16 arith mately age 11 years No difference in GBM thickness was observed metic mean measurements undertaken at least 3 6 m between males and females glomerular basement membrane thickness 018 1128 9Glomerular basement membrane GBM thickening is considered as one of the earliest detectable pathological features of diabetic nephropathy DN However whether the thickness of GBM will impact the prognosis of DN remains largely unknown of the normal range of glomerular basement membrane GBM thickness by electron microscopy is required for the diagnosis of thin basement membrane disease or
basement membrane thickness increases with surface area No difference in GBM thickness was observed between males and females The term in age 2 also was found to be non significant P 0 329 and was removed from the regression model glomerular basement membrane thickness of the normal range of glomerular basement membrane GBM thickness by electron microscopy is required for the diagnosis of thin basement membrane disease or ncbi nlm nih gov Indian J Nephrol v 18 2 2008 AprRayat CS Joshi K Sakhuja V Datta U Glomerular basement membrane thickness in normal adults and its application to the diagnosis of thin basement membrane disease an Indian study Indian J Pathol Microbiol 2005 48 453 8
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