anti glomerular basement membrane disease overviewJun 09 2017 Anti glomerular basement membrane anti GBM antibody disease is a rare autoimmune disorder in which circulating antibodies are directed against an antigen normally present in the GBM and alveolar basement membrane The target antigen is the alpha 3 chain of type IV collagen anti glomerular basement membrane disease glomerular basement membrane diseaseSpecialty RheumatologySynonyms Goodpasture s disease antiglomerular basement antibody disease anti GBM disease
glomerular basement membraneThe anti glomerular basement membrane anti GBM test looks for anti glomerular basement membrane antibodies that attack a part of the kidney known as the glomerular basement membrane GBM anti glomerular basement membrane disease international article S0085 2538 15 49500 6 An enzyme linked immunosorbent assay ELISA for anti glomerular basement membrane anti GBM antibodies was positive at 80 normal range 0 to 15 confirmed by positive binding on a Western blot using collagenase solubilized human GBM and microbiology Anti glomerular basement membrane antibody anti GBM disease or Goodpasture syndrome is a rare autoimmune disease characterized by the presence of autoantibodies directed against the NC1 domain of the alpha 3 chain of basement membrane collagen type IV
medlineplus gov Medical EncyclopediaThe glomerular basement membrane is the part of the kidney that helps filter waste and extra fluid from the blood Anti glomerular basement membrane antibodies are antibodies against this membrane They can lead to kidney damage anti glomerular basement membrane disease and microbiology Anti glomerular basement membrane antibody anti GBM disease or Goodpasture syndrome is a rare autoimmune disease characterized by the presence of autoantibodies directed against the NC1 domain of the alpha 3 chain of basement membrane collagen type IV
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